历史回顾

为什么医学研究委员会在1971年拒绝支持Rober Edwards和Patrick Stepoe对人类避孕的研究？

Why the Medical Research Council refused Robert Edwards and Patrick Steptoe support for research on human conception in 1971

观点

干细胞研究中的合作：诱导多能干细胞的案例

Complicity in stem cell research: the case of induced pluripotent stem cells

论著

男性学

胶质细胞系分化的神经因子基本由人类睾丸管周细胞产生，并可能在男性生精干细胞微环境中发挥作用

Glial cell line-derived neurotrophic factor is constitutively produced by human testicular peritubular cells and may contribute to the spermatogonial stem cell niche in man

人类精子中KIT酪氨酸激酶短缩形式的表达与精子DNA完整性有关

Expression of a truncated form of KIT tyrosine kinase in human spermatozoa correlates with sperm DNA integrity

早期妊娠

静脉用免疫球蛋白和特发性继发反复流产：一项多中心随机安慰剂对照研究

Intravenous immunoglobulin and idiopathic secondary recurrent miscarriage: a multicentered randomized placebo-controlled trial

一项创新性虚拟现实技术用于自动化人类胚胎体积测量

An innovative virtual reality technique for automated human embryonic volume measurements

钟形受体5的活化降低人类滋养细胞在体外对内膜细胞的附着

Activation of Toll-like receptor 5 decreases the attachment of human trophoblast cells to endometrial cells in vitro

人类胎盘BeWo细胞在循环性AMP依赖的功能性分化和合体化过程中，AMP（Epac）直接活化的交换蛋白的可能作用（BeWo细胞系：滋养细胞来源的人类绒癌细胞系）

Possible role of the exchange protein directly activated by cyclic AMP (Epac) in the cyclic AMP-dependent functional differentiation and syncytialization of human placental BeWo cells

胚胎学

卵子供应程序中卵子冷冻银行的应用：一项前瞻性、随机、对照临床研究

Use of cryo-banked oocytes in an ovum donation programme: a prospective, randomized, controlled, clinical trial

老鼠胚胎植入前脂联素（Adiponectin）受体表达和脂联素异构体作用（Adiponectin：一种脂肪组织分泌的多效性激素，可以调节和女性健康相关的肥胖负性作用，并且参与肥胖女性生殖力损害的过程）

Expression of adiponectin receptors and effects of adiponectin isoforms in mouse preimplantation embryos

生育控制

排卵前直接口服30mg的醋酸ulipristal可以显著推迟滤泡破裂（ulipristal acetate，UPA，用于紧急避孕的选择性孕激素受体调节剂。Ulipristal暂无中文译名，我建议翻为友立斯托，呵呵）

Immediate pre-ovulatory administration of 30 mg ulipristal acetate significantly delays follicular rupture

妇科学

女性粘膜下肌瘤术前GnRH激动剂治疗的价值：一项双盲安慰剂对照的随机研究

The value of pre-operative treatment with GnRH analogues in women with submucous fibroids: a double-blind, placebo-controlled randomized trial

有症状的合并肌瘤的女性其内膜细胞培养中GnRH抑制剂对细胞凋亡的上调作用

Up-regulation of apoptosis by gonadotrophin-releasing hormone agonist in cultures of endometrial cells from women with symptomatic myomas

附件扭转：术前诊断的预测评分

Adnexal torsion: a predictive score for pre-operative diagnosis

不育

澳大利亚和新西兰2004-2007年间辅助生育技术周期的比较分析

A comparative analysis of assisted reproductive technology cycles in Australia and New Zealand 2004–2007

高度反应性卵子供体应用两种激素刺激方案的前瞻性队列研究：对胚胎非整倍体和发育的影响

Prospective cohort study in high responder oocyte donors using two hormonal stimulation protocols: impact on embryo aneuploidy and development

对预期卵子供体加强遗传学和心理学检测行广泛筛查的必要性的评价

Evaluating the necessity for universal screening of prospective oocyte donors using enhanced genetic and psychological testing

生殖生物学

多囊卵巢患者卵子的生化和染色体分析

Metabolism and karyotype analysis of oocytes from patients with polycystic ovary syndrome

粘连素蛋白REC8、STAG3、SMC1β和SMC3的动力学与人类卵子减数分裂过程中姐妹染色单体凝聚中的作用一致

Dynamics of cohesin proteins REC8, STAG3, SMC1β and SMC3 are consistent with a role in sister chromatid cohesion during meiosis in human oocytes

生殖内分泌学

雌孕激素水平的降低与25-40岁女性能量缺乏有关

Estrogen and progesterone exposure is reduced in response to energy deficiency in women aged 25–40 years

生殖流行病学

孕期母亲酒精的消耗和男性后代的精子质量：20年的随访

Maternal alcohol consumption during pregnancy and semen quality in the male offspring: two decades of follow-up

双胎孕周和出生体重的长期趋势

Secular trends in gestational age and birthweight in twins

出生于SGA的年轻成人的生育力并没有改变

Fertility is not altered in young adults born small for gestational age

不育对于美国家庭规模的影响：来自国家家庭成长调查的数据

The impact of infertility on family size in the USA: data from the National Survey of Family Growth

乌克兰HIV感染的女性前次生育历史和产后计划生育

Previous reproductive history and post-natal family planning among HIV-infected women in Ukraine

生殖遗传学

预测人类卵子的非整倍体性：影响有丝分裂过程的关键因素

Predicting aneuploidy in human oocytes: key factors which affect the meiotic process

来自IVF和ICSI的人类胚胎表观遗传标志的评价

Evaluation of epigenetic marks in human embryos derived from IVF and ICSI

日本人群中构成性gr/gr删除的特征

Features of constitutive gr/gr deletion in a Japanese population